About Us
Bioinformat is Paulo Nuin — Principal Data Architect and Bioinformatician with 20+ years building production systems at the intersection of clinical genomics and modern AI. From CAP/CLIA-accredited diagnostic platforms to LLM-orchestrated genomics tooling, the practice lives equally in fullstack engineering and applied bioinformatics.
Expertise
Engineering & AI
- → Python, TypeScript, Rust, Swift, Clojure
- → React, SvelteKit, FastAPI, Django
- → Claude API, MCP servers, RAG, LLM fine-tuning
- → PostgreSQL, ClickHouse, CouchDB, DuckDB
- → AWS, Docker, Kafka & Dagster, CI/CD
Bioinformatics & Clinical
- → Clinical Genomics, NGS & proteomics
- → CAP / CLIA / ISO 15189 platforms
- → HL7 v2.3, Epic EMR integration
- → Variant calling, VCF, BLAST, CNV
- → Biostatistics, phylogenetics & population genetics
Background
Current work spans the clinical bioinformatics platform at Alberta Precision Laboratories (30+ production applications powering diagnostic reporting), architecture and engineering for the Alliance of Genome Resources and WormBase, and AI-engineering projects — from MCP servers and RAG pipelines to a fine-tuned code-review model — integrating Claude into genomics and software workflows.
Bioinformat takes on independent work for academic, biotech, and clinical clients — fullstack web applications, AI/LLM integrations, NGS pipelines, audit-grade data infrastructure, training, and consulting. Paulo is also the author of 30+ peer-reviewed publications, including a substantial cancer-biomarker record and the WormBase/Alliance consortium papers, listed on ORCID.